If you have followed Karl's journey with Multiple Myeloma you will know that he was diagnosed in March, 2017 and had a stem cell transplant in December of that same year. After the transplant Karl took an oral maintenance chemo, Lenolidamide, for 7 years and therefore was able to stay away from iv chemo. That changed in February of this year when he started iv chemo using Isatuxamab, Carfilzomib, and Dexamethasone. Karl's myeloma has historically mainly affected his monoclonal proteins (m-proteins), which are abnormal proteins produced in his body as a result of the cancer. At diagnosis his m-proteins were a little over 12. These were knocked down to half prior to the first stem cell transplant, and after the transplant were measured to be 1.5. These start growing again right away, but for Karl they grew exponentially. That is to say very slowly at first with a very low almost horizontal curve, and in the past year quickly with more of a vertical curve. In March of 2024 they ...
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